Who We Are
Program Administration
Ellis Neufeld, MD PhDProgram Director
Children's Hospital Boston
Dr. Ellis Neufeld earned his Bachelor’s degree in Chemistry and Biology from Wesleyan University in Middletown, Connecticut, in 1979, and his MD, PhD, in Medicine, Biochemistry, and Molecular Biology from Washington University School of Medicine in St. Louis, Missouri, in 1985. Dr. Neufeld spent his internship and residency at the Children’s Hospital Boston. He also spent his fellowship at CHB, where he was Fellow in Clinical Genetics, 1988, and Fellow in Hematology/Oncology from 1998-1990. Dr. Neufeld's bench-to-bedside research focuses on thiamine-responsive megaloblastic anemia (TRMA) syndrome, a rare inherited early-onset disorder that leads to anemia, diabetes, and progressive deafness, but can be ameliorated with high doses of thiamine (vitamin B1). Dr. Neufeld’s clinical research activities are numerous, including his role as Principal Investigator for two NHLBI clinical research network grants—the Transfusion Medicine Hemostasis Network and the Thalassemia Clinical Research Network. He also holds a K24 Mid-Career Investigator Award to support his mentoring activities in patient-oriented research. Dr. Neufeld currently serves as Associate Chief of the Hematology/Oncology Division of the Children’s Hospital Boston and Director of the Boston Hemophilia Center, and is the Egan Family Foundation Professor of Pediatrics at Harvard Medical School.
Program Coordinator
Children's Hospital Boston
Meghan Sullivan has been working in the Hematology Division of the Children's Hospital Boston for over three years. She received her B.A. in English from Bridgewater State College and is currently working on obtaining her Master of Social Work from Simmons College. She enjoys volunteering at Camp Sunshine in Casco, ME which is a retreat for children with life-threatening illnesses and their families.
K12 Site Directors
Kenneth Bauer, MDBeth Israel Deaconess Medical Center
Adult Hematology, Thrombosis/Hemostasis
Dr. Kenneth Bauer is Professor of Medicine, Harvard Medical School. His hospital positions include Director, Thrombosis Clinical Research, Beth Israel Deaconess Medical Center and Chief, Hematology Section, VA Boston Healthcare System. Dr Bauer received his medical degree from Stanford University School of Medicine in Stanford, California. He completed his residency in medicine at the University of Chicago Hospitals and Clinics in Illinois. He was a Fellow in Medical Oncology and a Clinical/Research Fellow in the Division of Thrombosis and Hemostasis at Dana Farber Cancer Institute and was also a Clinical/Research Fellow in the Hematology-Oncology Division at Beth Israel Hospital, Boston, Massachusetts. Dr Bauer’s research interests include development and clinical evaluation of sensitive new assays for the detection of hypercoagulable states, definition and elucidation of the mechanisms leading to the development of a prethrombotic state, and clinical evaluation of new antithrombotic drugs. Dr Bauer served as immediate past-Chairman of the Council of the International Society on Thrombosis and Haemostasis (ISTH) and was previously Chairman of the Subcommittee on Predictive Haemostatic Variables in Vascular Diseases of the ISTH. Dr Bauer has published over 200 original reports, reviews, and book chapters.
Leslie Silberstein, MDCenter for Blood Research Institute
Pediatric and Adult Transfusion Medicine
Dr. Leslie Silberstein received the Baccalaureate and M.D. Degrees from the University of Leiden, the Netherlands, and had post-graduate training in Hematology/Oncology and Transfusion Medicine at Tufts-New England Medical Center in Boston, MA. He is currently a Professor of Pathology at Harvard Medical School and Director of the Joint Program in Transfusion Medicine at Children's Hospital, Boston, Brigham and Women’s Hospital, and the Dana-Farber Cancer Institute. He is also a Senior Investigator and Director of the Center for Human Cell Therapy at the CBR Institute for Biomedical Research. The overall theme of Dr. Silberstein’s research laboratory pertains to the role(s) of chemokines in the bone marrow environment. This research is funded in part by a program project grant, “Adhesion Molecules in Transfusion Medicine”, of which Denisa Wagner is the principal investigator.
Ellis Neufeld, MD, PhD
Children's Hospital Boston
Pediatric Hematology, Pediatric and Adult Hemophilia and Thalassemia
Edward Benz, MD/James Griffin, MD, co-Site DirectorsDana Farber Cancer Institute
Adult Hematology, Red Cell Biology, Growth Factor Biology
Dr. Edward J. Benz, Jr is president and chief executive officer of Dana-Farber Cancer Institute and Dana-Farber/Partners Cancer Care as well as Principal Investigator and Director of Dana-Farber/Harvard Cancer Center and a member of the Governing Board of Dana-Farber/Children's Hospital Cancer Center. He is also the Richard and Susan Smith Professor of Medicine and a Professor of Pediatrics, and Professor of Pathology at Harvard Medical School. He is a graduate of Princeton University and Harvard Medical School. An internationally recognized hematologist, Dr. Benz received his training at Brigham and Women's Hospital and the National Institutes of Health. Board certified in internal medicine and hematology, Dr. Benz is an expert in inherited anemias and diseases of the red cell, and the red cell membrane cytoskeleton. Dr. Benz is president-elect to the Association of American Cancer Institutes and is currently the co-chair of the NIH Advisory Board for Clinical Research. He continues to be an active NIH funded investigator whose laboratory studies the molecular pathology of red cell disorders. He is the author of over 200 scientific books, papers, and abstracts.
David Kuter, MD, DPhilMass. General Hospital
Adult Hematology, Thrombosis and Hemostasis
Dr. David J. Kuter earned a research doctorate (DPhil) at Magdalen College of Oxford University and a medical degree at Harvard Medical School. Dr. Kuter holds appointments as Associate Professor of Medicine at Harvard Medical School and Associate Professor of Health Sciences and Technology at the Massachusetts Institute of Technology. Dr. Kuter is board certified in internal medicine, hematology, and medical oncology. Dr. Kuter has research efforts researching coagulopathies, anticoagulation, and platelet disorders. In recent years, Dr. Kuter has conducted basic and clinical research into the development of effective thrombopoietic agents. He is Director of Clinical Hematology at the Massachusetts General Hospital, Director of the MGH Gaucher’s Treatment Center, and Program Director for Hematology at MGH/Partners/DFCI. He has overseen hematology training for the Hematology/Oncology Fellows at MGH for over two decades.
Advisory Committee Members
Nancy Berliner, MDBrigham and Women's Hospital
Dr. Berliner earned her Bachelor’s degree from Yale College and her MD from Yale Medical School. She then obtained training as a Resident in Internal Medicine, Internal Medicine Chief Resident, and Hematology Fellow at the Brigham and Women’s Hospital in Boston, MA. She then spent 20 years on the faculty of the Yale University School of Medicine, where she rose through the ranks to Professor of Internal Medicine and Genetics. In January, 2007, Dr. Berliner returned to the Brigham where she is Chief of Hematology and Professor of Medicine at Harvard Medical School. Dr. Berliner has broad clinical interests in both classical hematology and hematologic malignancies. Her research is focused on the regulation of neutrophil-specific gene expression and its disruption in myelodysplasia and acute leukemia. More recently she has also initiated studies of the role of inflammatory cytokines in the pathogenesis of anemia in the elderly. She is currently Vice President of the American Society of Hematology, and will be ASH President in 2009.
David G. Nathan, MDDana-Farber Cancer Institute, Children’s Hospital
Aplastic Anemias, Hemoglobinopathies and Hemolytic Anemias
Dr. David G. Nathan is a graduate of Harvard College (1951) and Harvard Medical School (1955). He was an intern and senior resident in medicine at the then Peter Bent Brigham Hospital and a Clinical Associate at the National Cancer Institute. From 1959 to 1966 he was a hematologist at the Peter Bent Brigham Hospital and then became Chief of the Division of Hematology and Oncology at Children's Hospital and Dana-Farber Cancer Institute. From 1985 to 1995 he was Physician-in-Chief of the Children's Hospital and from 1995 to 2000 was President of Dana Farber Cancer Institute. Dr. Nathan's research has focused on the inherited disorders of red cells and granulocytes and particularly on thalassemia. He has trained over 100 hematologists many of whom hold leading positions in pediatrics and internal medicine. His text book entitled Hematology of Infancy and Childhood is the leading text in the field. He is the author of two popular books: Genes Blood and Courage published by the Harvard University Press in 1995, and Smart Drugs: Attacking Cancer in the 21st century, to be published by John Wiley in 2007. Dr. Nathan is a member of the American Society for Clinical Investigation, the Association of American Physicians, the American Pediatric Society, the Institute of Medicine, the American Academy of Arts and Sciences and the American Philosophical Society.
Peter Newburger, MDUMass Memorial Medical Center
Dr. Peter Newburger earned his B.S. degree in chemistry from Haverford College, Haverford, PA, in 1970, and his MD from Harvard Medical School (cum laude in immunology) in 1974. After internship and residency at Children’s Hospital, Boston, he trained in pediatric hematology and oncology at the (then) Sidney Farber Cancer Center and Children’s Hospital, Boston from 1976 to 1979. He served on the faculty at Harvard Medical School and Children’s Hospital for two years, then moved to the University of Massachusetts Medical School in 1981 to establish the medical center’s first pediatric hematology/oncology division, which he has directed since 1981. He is currently the Ali and John Pierce Professor of Pediatric Hematology/Oncology, as well as Vice Chair and Director of Research for the Department of Pediatrics, at UMass Medical School. He has served as a member of NIH hematology study sections virtually every year since 1986. He is a member of the Sub-Board of Pediatric Hematology/Oncology of the American Board of Pediatrics, associate editor of Pediatric Blood and Cancer, and member of the editorial boards of Blood (past), American Journal of Hematology, and Current Opinion in Hematology. His laboratory research focuses on leukocyte gene expression and disorders of phagocyte function, and he directs clinical research on neutropenia through membership on the executive committee of the Severe Chronic Neutropenia International Registry.
Kenneth A. Bauer, MD
Beth Israel Deaconess
Disorders of Hemostasis, Thrombophilia and Venous Thrombosis
David J. Kuter, MD DPhil
Massachusetts General Hospital
Disorders of Hemostasis, Thrombophilia and Venous Thrombosis
Leslie E. Silberstein, MD
CBR Institute, Children’s Hospital, Joint Program in Transfusion Medicine
Pediatric Transfusion Medicine and Cell–based Therapies
Richard M. Stone, MDDana-Farber Cancer Institute
Myeloproliferative Disorders and Myelodysplastic Syndromes
Dr. Richard Maury Stone is Clinical Director of the Adult Leukemia Program at the Dana-Farber Cancer Institute, an attending physician at Brigham and Women’s Hospital and Associate Professor of Medicine at Harvard Medical School in Boston, Massachusetts. Dr. Stone cares for patients with acute and chronic leukemias, myelodysplasia and myeloproliferative disorders. Dr. Stone conducts clinical and translational research with the goal of deriving better outcomes for patients with these disorders. His laboratory research focuses on the mechanism of leukemic cell differentiation, with the ultimate goal of producing new cancer therapies. Dr. Stone earned his AB in Biochemistry at Harvard Medical College in Cambridge, Massachusetts and his MD at Harvard Medical School in Boston. After graduating, he completed his internship and residencies in Internal Medicine at Brigham and Women’s Hospital in Boston, where he was designated Chief Medical Resident. Dr. Stone trained as a Fellow in Medical Oncology at the Dana-Farber Cancer Institute.
Leslie Kalish, ScD, ex officioBiostatistics core, Clinical Research Program Children’s Hospital
Biostatistics, Training
Dr. Leslie Kalish’s professional career has focused on the design, implementation and analysis of clinical trials, epidemiologic studies, and other clinical investigations. His statistical research has been in the application of optimal statistical design methodology to treatment allocation procedures for clinical trials and to selection of control groups in observational epidemiologic studies. Dr. Kalish has collaborated on research in transfusion medicine, HIV and infectious diseases, immunology, oncology, alternative medicine, and other fields. He had leadership roles in the coordinating centers of several NIH-funded cohort studies and clinical trials, including as the original principal investigator of the coordinating center of the Transfusion Medicine/Hemostasis Clinical Trials Network. Dr. Kalish joined the Clinical Research Program at Children's Hospital Boston in 2003, where he continues to provide mentoring and analytic expertise to researchers in study design, protocol development, and grant-writing. He conducts or directs statistical data analyses for a variety of projects.
Scholars
Deb Chirnomas, MDDr. Deborah Chirnomas, received her BA from Penn., and her MD from Albert Einstein. She was a fellow at Children's Hospital Boston 2002-2005 and is currently an Instructor in Pediatrics at Harvard Medical School. She serves as the Associate Director of the Thalassemia Program at Children's Hospital Boston. She is also pursuing a Master's in Public Health from the Harvard School of Public Health. Dr. Chirnomas' research project for the K12 Program focuses on research regarding patients who have inadequate response to deferasirox.
Matthew Heeney, MD
Dr. Matthew Heeney received his B.Sc. From Trinity College, received his MD from the University of Calgary. He was a fellow at Duke University Medical Center. Currently Dr. Heeney is an Assistant Professor in Pediatrics at Harvard Medical School and Director of the Hematology Clinic at Children's Hospital Boston. Dr. Heeney plans to pursue his Master's of Medical Science through the Harvard Medical School's K30 Program. Dr. Heeney's research project focuses on looking for the genetic basis of unexplained microcytosis and iron-resistant iron deficiency.
Dr. Maureen Okam received her MD from the University of Port Harcourt, Nigeria, and her MPH from the Harvard School of Public Health. She was a fellow in Hematology and Medical Oncology at Yale School of Medicine. Currently Dr. Okam is an Associate Physician in the Hematology Division of the Brigham and Women's Hospital. Dr. Okam's research project focuses on the development of new agents for the treatment of hemoglobinopathies - sickle cell disease and thalassemia. Her immediate focus is the evaluation of histone deacetylase inhibitors in the induction of fetal hemoglobin.
Gregory Abel, MD, MPHDr. Gregory (“Goyo”) Abel received his MD and his MPH from Columbia University. He trained in internal medicine at the Massachusetts General Hospital, and went on to complete his fellowship in Hematology and Medical Oncology at the combined program of the Dana-Farber Cancer Institute, the Massachusetts General Hospital and the Brigham and Women’s Hospital. Dr. Abel is currently on staff at the Dana-Farber Cancer Institute, where he works as a hematology-focused health services researcher in the Center for Outcomes and Policy Research. Dr. Abel’s research project focuses on the assessment of patterns of care and quality of care for elderly patients with the myelodysplastic syndrome.
Ann Mullally, MDDr. Ann Mullally received her MD from University College Dublin, Ireland. She completed residency in internal medicine at Johns Hopkins and fellowship in hematology/oncology at the Dana Faber Cancer Institute /Massachusetts General Hospital combined program. She is currently a research fellow in the laboratory of Dr. Benjamin Ebert at Brigham & Women’s Hospital in Boston and an Instructor in Medicine at Harvard Medical School. Dr. Mullally’s research bridges the “bench” and the ”bedside” by addressing clinically relevant questions that directly affect patients with myeloproliferative neoplasms (MPN). She employs mouse models of MPN as a tool to further our understanding of the biology of these diseases in humans and to inform clinical trial design and therapeutic approaches to patients with MPN.
Erica Esrick, MDDr. Erica Esrick received her BA from Dartmouth College, and her MD from Harvard Medical School. She completed her fellowship in Pediatric Hematology/Oncology at Children’s Hospital Boston and Dana-Farber in 2010. She is an Instructor in Pediatrics at Harvard Medical School, and she is currently a research fellow in the laboratory of Dr. Benjamin Ebert. Dr. Esrick’s research project for the K12 Program focuses on the preclinical development of histone deacetylase inhibitors as fetal hemoglobin induction agents. Her current projects involve testing HDAC inhibitors in primate, murine, and in vitro models. The overall goal of this project is to develop new effective treatment options for patients with sickle cell disease and thalassemia.

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